Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592483 | 0.83 | MAPT (0.49) | MAPTSMN1; SMN2HTTLMNAHSD17B10 | |
| SCHEMBL29280657 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL29280655 | 0.79 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2MMP12ALDH1A1MEN1 | |
| SCHEMBL14838657 | 0.78 | DUT (0.42) | LMNAHSD17B10TSHRHDAC3HDAC4 | |
| SCHEMBL11573154 | 0.77 | KDM4E (0.52) | MAPTSMN1; SMN2HTTLMNAHSD17B10 | |
| Water SCHEMBL11565814 | 0.77 | MAPT (0.50) | MAPTSMN1; SMN2HTTLMNATSHR | |
| SCHEMBL11725068 | 0.76 | TP53 (0.46) | MAPTLMNAALDH1A1GAA | |
| SCHEMBL6153940 | 0.75 | ALDH1A1 (0.50) | MAPTSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL6154638 | 0.75 | ALDH1A1 (0.50) | MAPTSMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL6153937 | 0.75 | ALDH1A1 (0.50) | MAPTSMN1; SMN2HTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060544-A | COUPLERS | GAF CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4039524-A | Keto-amido containing phenylazo benzothiazole dyestuffs | GAF CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3931145-A | POLYESTER | GAF CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |