Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11565814 | 0.86 | MAPT (0.50) | ALOX12LMNAMAPT | |
| SCHEMBL11568718 | 0.77 | NPC1 (0.48) | MAPT | |
| SCHEMBL11957636 | 0.77 | POLB (0.55) | LMNAL3MBTL1MAPT | |
| SCHEMBL11674847 | 0.76 | MAPT (0.47) | GAAALDH1A1LMNAMAPT | |
| SCHEMBL11570598 | 0.75 | MAPT (0.51) | MAPT | |
| SCHEMBL11574421 | 0.74 | TDP1 (0.51) | GAAALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL3364884 | 0.73 | POLB (0.60) | LMNAL3MBTL1MAPT | |
| SCHEMBL11800387 | 0.73 | HPGD (0.51) | TP53GAAALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7088180 | 0.71 | POLB (0.52) | MAPT | |
| SCHEMBL11574037 | 0.71 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064252-A | ARTERIOSCLEROSIS | NIPPON SHINYAKU CO., LTD. (JA) | 1977-12-20 | — | — | US | disclosed |