SCHEMBL11675474

SCHEMBL11675474

CCN(c1cccc(OC)c1)C(C)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.49
TAAR1 Q96RJ0 3/20 0.44
CASR P41180 1/20 0.42
MTNR1A P48039 4/20 0.41
MTNR1B P49286 4/20 0.41
CALM1 P0DP23 1/20 0.41
CAMKK2 Q96RR4 1/20 0.41
ESR1 P03372 1/20 0.41
CETP P11597 1/20 0.41
ABCB1 P08183 1/20 0.40
HTR1A P08908 1/20 0.40
DRD2 P14416 1/20 0.40
IDO1 P14902 1/20 0.40
AGXT P21549 1/20 0.40
BCHE P06276 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11676107 0.89 TAAR1 (0.42) MAOBTAAR1ESR1IDO1
SCHEMBL11675958 0.85 AOC3 (0.45) ABCB1IDO1AGXTBCHE
SCHEMBL11676858 0.85 TAAR1 (0.46) MAOBTAAR1CASRMTNR1AMTNR1B
SCHEMBL8767732 0.84 TSHR (0.42) TAAR1HTR1AIDO1BCHE
SCHEMBL11679587 0.84 TP53 (0.44) IDO1BCHE
SCHEMBL11676389 0.83 TAAR1 (0.41) TAAR1IDO1AGXT
SCHEMBL11675922 0.82 LTA4H (0.49) MAOBTAAR1CASRMTNR1AMTNR1B
SCHEMBL11677528 0.80 BCHE (0.53) MAOBBCHE
SCHEMBL11677449 0.79 ABCB1 (0.42) MAOBTAAR1CASRABCB1HTR1A
SCHEMBL11676731 0.79 TAAR1 (0.46) TAAR1CASRMTNR1AMTNR1BESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4051117-A Triazole-azo-phenyl cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed
US-4051084-A BENZOTHIAZOLE BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed