Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677439 | 0.89 | KDM4E (0.44) | TSHRCYP1A2CYP2D6CYP2C19RAB9A | |
| SCHEMBL11677510 | 0.87 | TDP1 (0.46) | TSHRL3MBTL1CYP2D6CYP2C19RAB9A | |
| SCHEMBL11678142 | 0.85 | L3MBTL1 (0.42) | TSHRL3MBTL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11677855 | 0.84 | HTR1A (0.38) | LMNASMN1; SMN2ALDH1A1DRD2CRHBP | |
| SCHEMBL11674855 | 0.84 | L3MBTL1 (0.41) | L3MBTL1DRD2HTR1AHTR7HTR2A | |
| SCHEMBL11680703 | 0.83 | DRD2 (0.45) | L3MBTL1LMNASMN1; SMN2DRD2DRD4 | |
| SCHEMBL10887269 | 0.83 | CRHBP (0.40) | ALDH1A1DRD2DRD4GAACRHBP | |
| SCHEMBL11675411 | 0.82 | HRH1 (0.49) | TSHRL3MBTL1CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL11786430 | 0.81 | NPC1 (0.46) | L3MBTL1CYP1A2CYP2D6CYP2C19RAB9A | |
| SCHEMBL11431614 | 0.81 | CRHBP (0.43) | TSHRLMNASMN1; SMN2ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4000141-A | SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |