Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798123 | 0.86 | ALDH1A1 (0.43) | KDM4EL3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL11677849 | 0.82 | L3MBTL1 (0.56) | KDM4EL3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL11554619 | 0.81 | ALDH1A1 (0.41) | KDM4EL3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL11751166 | 0.80 | SLC6A3 (0.45) | KDM4EL3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL11677514 | 0.77 | MAPT (0.53) | KDM4EL3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL11678598 | 0.76 | L3MBTL1 (0.72) | KDM4EL3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL11675968 | 0.76 | L3MBTL1 (0.58) | KDM4EL3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL11678574 | 0.75 | KDM4E (0.54) | KDM4EL3MBTL1MAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL11679014 | 0.75 | L3MBTL1 (0.70) | KDM4EL3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL11678584 | 0.75 | KDM4E (0.62) | KDM4EL3MBTL1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |