Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16002892 | 0.83 | FTO (0.57) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL1626273 | 0.81 | CA2 (0.56) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL25754637 | 0.81 | NSD2 (0.56) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL8328504 | 0.80 | NSD2 (0.52) | TSHRCYP3A4NFKB1THPOLMNA | |
| SCHEMBL18862467 | 0.80 | KDM4E (0.60) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL16000113 | 0.80 | LMNA (0.50) | TSHRCYP3A4NFKB1THPOHIF1A | |
| Hydrochloric Acid SCHEMBL28991653 | 0.79 | CA2 (0.55) | TSHRCYP3A4NFKB1THPOHIF1A | |
| Hydrochloric Acid SCHEMBL30639813 | 0.79 | CYP3A4 (0.60) | TSHRCYP3A4NFKB1THPOHIF1A | |
| Hydrochloric Acid SCHEMBL27202570 | 0.79 | CYP3A4 (0.60) | TSHRCYP3A4NFKB1THPOHIF1A | |
| SCHEMBL14785388 | 0.78 | MEN1 (0.56) | TSHRCYP3A4NFKB1THPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061639-A | MICROBIOCIDES | THE DOW CHEMICAL COMPANY (US) | 1977-12-06 | — | — | US | disclosed |