SCHEMBL8328504

SCHEMBL8328504

NNS(=O)(=O)c1cccc2c(S(=O)(=O)NN)cccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 8/20 0.52
CYP3A4 P08684 5/20 0.47
CYP1A2 P05177 4/20 0.47
CYP2D6 P10635 4/20 0.47
CYP2C9 P11712 4/20 0.47
CYP2C19 P33261 4/20 0.47
FPR2 P25090 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MTOR P42345 1/20 0.47
CSNK1A1 P48729 1/20 0.47
MYLK Q15746 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CDK2 P24941 1/20 0.47
TP53 P04637 4/20 0.46
THPO P40225 3/20 0.46
NFKB1 P19838 2/20 0.46
PMP22 Q01453 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
APEX1 P27695 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10991218 0.91 LDHA (0.47) NSD2CYP3A4CYP1A2CYP2D6CYP2C9
SCHEMBL30442076 0.87 CA2 (0.62) CYP3A4CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL419323 0.87 CA2 (0.62) CYP3A4CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL235824 0.84 CA2 (0.68) NSD2CYP1A2CYP2C19KDM4EHSD17B10
SCHEMBL23753961 0.82 CA2 (0.66) NSD2CYP1A2CYP2C19KDM4EHSD17B10
SCHEMBL1427884 0.82 CA1 (0.48) CYP2C9CA1CA2CA9MEN1
SCHEMBL235825 0.81 NSD2 (0.53) NSD2TTR
Cyclopropane SCHEMBL12502165 0.80 CA2 (0.62) NSD2CYP1A2CYP2C19KDM4EHSD17B10
SCHEMBL11679031 0.80 TSHR (0.50) CYP3A4KDM4ETP53THPONFKB1
SCHEMBL30437454 0.77 HTR6 (0.49) NSD2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192218-B1 PRINTABLE COMPOSITION FOR MAKING EMBOSSED DECORATIVE SHEETS CONGOLEUM CORPORATION (US) 1991-08-07 EP claimed
CN-86101786-A Produce the printable composition of embossed decorative sheets 1986-11-05 CN claimed
EP-0192218-A2 Printable composition for making embossed decorative sheets CONGOLEUM CORPORATION (US) 1986-08-27 EP claimed
US-3966651-A Process for the production of fine-cell polyolefin foams BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed
US-5858160-A Decorative surface coverings containing embossed-in-register inlaids CONGOLEUM CORPORATION (US) 1999-01-12 US disclosed
EP-0192218-B1 PRINTABLE COMPOSITION FOR MAKING EMBOSSED DECORATIVE SHEETS CONGOLEUM CORPORATION (US) 1991-08-07 EP disclosed
CN-1010666-B Method for producing thermoplastic resin sheet CONGONLEUM CORP (US) 1990-12-05 CN disclosed
US-4844849-A BLOWING AGENT BETWEEN THERMOPLASTIC SHEETS; HEATING TO DECOMPOSE CONGOLEUM CORPORATION (US) 1989-07-04 US disclosed
CN-86101786-A Produce the printable composition of embossed decorative sheets 1986-11-05 CN disclosed
EP-0192218-A2 Printable composition for making embossed decorative sheets CONGOLEUM CORPORATION (US) 1986-08-27 EP disclosed
US-4521542-A Arylsulphonyl hydrazones as blowing agents BAYER AKTIENGESELLSCHAFT (DE) 1985-06-04 US disclosed
US-4277427-A DISTRIBUTION OF RESINOUS FLAKES CONTAINING A BLOWING AGENT SUPPRESSOR ON A PRINTED, GELLED, FOAMABLE POLYMER CONGOLEUM CORPORATION (US) 1981-07-07 US disclosed
US-4264643-A COATING WITH ACETIC ACID BEFORE APPLYING THE UNCURED POLYURETHANE CONGOLEUM CORPORATION (US) 1981-04-28 US disclosed
US-3966651-A Process for the production of fine-cell polyolefin foams BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3943018-A Decorative surface coverings CONGOLEUM INDUSTRIES, INC. (US) 1976-03-09 US disclosed