SCHEMBL8435490

SCHEMBL8435490

CCOC(C)N(CC)c1cccc(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
TP53 P04637 2/20 0.42
POLQ O75417 2/20 0.39
HTT P42858 3/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 2/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 6/20 0.36
NPSR1 Q6W5P4 2/20 0.36
NPC1 O15118 2/20 0.36
GPX4 P36969 1/20 0.36
RAB9A P51151 1/20 0.36
PAX8 Q06710 1/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
GAA P10253 2/20 0.36
LMNA P02545 1/20 0.36
GLA P06280 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11321042 0.85 MAPT (0.43) MAPTTP53POLQHTTMEN1
SCHEMBL8435801 0.85 ALDH1A1 (0.44) MAPTTP53POLQHTTPOLB
SCHEMBL8438006 0.85 TP53 (0.39) MAPTTP53POLQHTTMEN1
SCHEMBL17101219 0.85 MAPT (0.39) MAPTTP53POLQHTTMEN1
SCHEMBL11679587 0.84 TP53 (0.44) MAPTTP53HTTMEN1KMT2A
SCHEMBL11674444 0.83 HSD17B1 (0.42) MAPTTP53POLQHPGDLMNA
SCHEMBL28648836 0.82 TP53 (0.40) MAPTTP53POLQHTTMEN1
SCHEMBL11676404 0.81 HSD17B1 (0.42) MAPTTP53POLQHTTMEN1
SCHEMBL11675526 0.81 MAPT (0.46) MAPTTP53POLQHTTMEN1
SCHEMBL17101217 0.81 MAPT (0.41) MAPTTP53POLQHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114806212-A Brilliant blue disperse dye compound, mixture, composition, preparation method and application thereof 乐平市赛复乐医药化工有限公司 2022-07-29 CN disclosed
US-5883232-A DIAZAHEMICYANINE, TRIAZOLE, AZO AND HYDROPHOBIC DYES; COLORFASTNESS, COLOR REPRODUCIBILITY SONY CORPORATION (JP) 1999-03-16 US disclosed
US-5834600-A DIAZAHEMICYANINE DYES, MAGENTA, IMPROVED PHOTOSTABILITY AND REPRODUCIBILITY SONY CORPORATION (JP) 1998-11-10 US disclosed
EP-0751188-B1 Hydrophobic cationic dyes and thermal transfer ink ribbons using the same SONY CORP (JP) 1998-08-26 EP disclosed
EP-0751188-A1 Hydrophobic cationic dyes and thermal transfer ink ribbons using the same SONY CORPORATION (JP) 1997-01-02 EP disclosed
US-4898941-A Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-02-06 US disclosed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed