Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11675200 | 0.90 | TAAR1 (0.41) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL11679587 | 0.88 | TP53 (0.44) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL11690661 | 0.85 | CHRNB2 (0.46) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL11676107 | 0.85 | TAAR1 (0.42) | KDM4EALDH1A1LMNAIDO1HTT | |
| SCHEMBL11677223 | 0.83 | LMNA (0.42) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL11676389 | 0.82 | TAAR1 (0.41) | MAPTIDO1S1PR1 | |
| SCHEMBL8435490 | 0.81 | MAPT (0.42) | ALDH1A1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL11677195 | 0.80 | IDO1 (0.44) | ALDH1A1POLBMAPTTP53IDO1 | |
| SCHEMBL11676201 | 0.78 | AGXT (0.37) | POLBCNR1CNR2SMN1; SMN2 | |
| SCHEMBL11677494 | 0.77 | NOS2 (0.39) | KDM4EALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |