Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064868 | 0.92 | LMNA (0.67) | LMNAMAPTRECQLL3MBTL1TSHR | |
| SCHEMBL13096315 | 0.88 | MAPK1 (0.61) | LMNAMAPTCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11685551 | 0.88 | LMNA (0.58) | LMNAMAPTRECQLL3MBTL1TSHR | |
| SCHEMBL11686021 | 0.88 | LMNA (0.58) | LMNAMAPTRECQLL3MBTL1TSHR | |
| SCHEMBL14064866 | 0.88 | LMNA (0.52) | LMNAMAPTRECQLL3MBTL1TSHR | |
| SCHEMBL19669063 | 0.84 | PKM (0.59) | LMNAMAPTRECQLL3MBTL1TSHR | |
| SCHEMBL11678813 | 0.82 | LMNA (0.58) | LMNAMAPTRECQLL3MBTL1TSHR | |
| SCHEMBL4367726 | 0.82 | LMNA (0.56) | LMNAMAPTRECQLL3MBTL1TSHR | |
| SCHEMBL19558295 | 0.81 | ALDH1A1 (0.54) | LMNAMAPTRECQLTSHRKDM4E | |
| SCHEMBL166337 | 0.81 | LMNA (0.64) | LMNAMAPTRECQLL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9214345-B2 | Film-forming composition and ion implantation method | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-12-15 | — | — | US | disclosed |
| US-9214345-B2 | Film-forming composition and ion implantation method | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-12-15 | — | — | US | disclosed |
| US-4048102-A | CROSSLINKING, MENTHANEDIAMINE, ISOPHORONEDIAMINE | THE DOW CHEMICAL COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4007139-A | 2,4-DIKETO-1,3,5-HEXAHYDRO-TRIAZINE | THE DOW CHEMICAL COMPANY (US) | 1977-02-08 | — | — | US | disclosed |