SCHEMBL4367726

SCHEMBL4367726

C=CCn1c(=O)n(CC=C)c(=O)n(CC(O)COc2ccccc2)c1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.56
HTT P42858 2/20 0.56
MAPT P10636 2/20 0.55
RECQL P46063 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 2/20 0.49
TSHR P16473 2/20 0.48
HIF1A Q16665 2/20 0.48
CYP2D6 P10635 2/20 0.48
ALDH1A1 P00352 1/20 0.47
SLC5A2 P31639 1/20 0.47
PLA2G4A P47712 2/20 0.47
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14064868 0.89 LMNA (0.67) LMNAHTTMAPTRECQLL3MBTL1
SCHEMBL11678813 0.82 LMNA (0.58) LMNAHTTMAPTRECQLL3MBTL1
SCHEMBL11686021 0.82 LMNA (0.58) LMNAHTTMAPTRECQLL3MBTL1
SCHEMBL11680313 0.82 LMNA (0.58) LMNAHTTMAPTRECQLL3MBTL1
SCHEMBL11685551 0.82 LMNA (0.58) LMNAHTTMAPTRECQLL3MBTL1
SCHEMBL17749634 0.81 LMNA (0.83) LMNAHTTMAPTRECQLTSHR
SCHEMBL19669063 0.80 PKM (0.59) LMNAMAPTRECQLL3MBTL1KDM4E
SCHEMBL27424952 0.80 LMNA (0.45) LMNAHTTMAPTRECQLL3MBTL1
SCHEMBL24495872 0.77 CYP3A4 (0.67) LMNAHTTMAPTTSHRCYP2D6
SCHEMBL13286724 0.77 CYP3A4 (0.67) LMNAHTTMAPTTSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090283308-A1 Curable Resin Composition and Use Thereof ZEON CORPORATION (JP) 2009-11-19 US disclosed
US-7396588-B2 Curable composition, varnish and laminate ZEON CORPORATION (JP) 2008-07-08 US disclosed
US-7332229-B2 Varnish, shaped item, electrical insulating film, laminate, flame retardant slurry and process for producing flame retardant particles and varnish ZEON CORPORATION (JP) 2008-02-19 US disclosed
US-20080029476-A1 Circuit Board And Manufacturing Method Thereof ZEON CORPORATION (JP) 2008-02-07 US disclosed
US-20070060674-A1 Curable composition, varnish and laminate ZEON CORPRATION (JP) 2007-03-15 US disclosed
US-7160609-B2 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2007-01-09 US disclosed
US-20050159509-A1 Varnish, shaped item, electrical insulating film, laminate, flame retardant slurry and process for producing flame retardant particles and varnish ZEON CORPORATION (JP) 2005-07-21 US disclosed
US-20040025743-A1 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2004-02-12 US disclosed
US-6310140-B1 Thermoplastic elastomers of good dyeability and high strength and elasticity as well as impact-resistant polymer blends produced therefrom BOREALIS GMBH (AT) 2001-10-30 US disclosed