Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11680343 | 0.98 | MAPT (0.53) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL11677381 | 0.83 | RAB9A (0.50) | MAPTRAB9ANPC1KDM4EHSD17B1 | |
| SCHEMBL11818226 | 0.83 | MAPT (0.48) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL11801974 | 0.83 | MAPT (0.48) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11678026 | 0.82 | MAPT (0.56) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL11678301 | 0.82 | L3MBTL1 (0.49) | MAPTRAB9ANPC1KDM4EHSD17B1 | |
| SCHEMBL11801251 | 0.82 | ALDH1A1 (0.43) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11873000 | 0.81 | MAPT (0.46) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL11677892 | 0.79 | MAPT (0.53) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL15106223 | 0.78 | NPC1 (0.58) | MAPTRAB9ANPC1KDM4EHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-3947593-A | ANTIVIRUL AGENTS | RICHARDSON-MERRELL INC. (US) | 1976-03-30 | — | — | US | claimed |
| US-3983124-A | ANTIVIRAL AGENTS | RICHARDSON-MERRELL INC. (US) | 1976-09-28 | — | — | US | disclosed |