Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.37 |
| ▸ | WNT3A | P56704 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801974 | 0.95 | MAPT (0.48) | ALDH1A1MAPTKDM4EAGTR1HPGD | |
| SCHEMBL11836659 | 0.88 | HPGD (0.44) | ALDH1A1KDM4EHPGDATMCTNNB1 | |
| SCHEMBL11733570 | 0.82 | HPGD (0.44) | HPGDATMCTNNB1WNT3APKM | |
| SCHEMBL11680467 | 0.82 | MAPT (0.54) | ALDH1A1MAPTKDM4EAGTR1NPC1 | |
| SCHEMBL11794930 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EHPGDATM | |
| Hydrochloric Acid SCHEMBL11680343 | 0.80 | MAPT (0.53) | ALDH1A1MAPTKDM4EAGTR1NPC1 | |
| Hydrochloric Acid SCHEMBL11845401 | 0.80 | HPGD (0.43) | ALDH1A1MAPTHPGDATMCTNNB1 | |
| SCHEMBL11729358 | 0.80 | L3MBTL1 (0.43) | ALDH1A1MAPTKDM4EHPGDATM | |
| Hydrochloric Acid SCHEMBL11797777 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHPGDATM | |
| SCHEMBL11832428 | 0.79 | HPGD (0.42) | ALDH1A1MAPTKDM4EHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |