Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433150 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1GAACDC7 | |
| Methane SCHEMBL11679474 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1GAACDC7 | |
| SCHEMBL14776438 | 0.83 | HPGDS (0.41) | SMN1; SMN2RAB9ANPC1LMNAPOLB | |
| SCHEMBL4461793 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMEN1GAACDC7 | |
| Hydrochloric Acid SCHEMBL3972316 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1GAACDC7 | |
| SCHEMBL9980434 | 0.79 | GPR119 (0.39) | SMN1; SMN2KMT2ARAB9ANPC1GPR119 | |
| SCHEMBL12877954 | 0.78 | HPGDS (0.45) | — | |
| SCHEMBL17765329 | 0.78 | POLB (0.43) | SMN1; SMN2KMT2AMEN1GAALMNA | |
| SCHEMBL27557993 | 0.78 | LMNA (0.44) | SMN1; SMN2KMT2AGAARAB9ANPC1 | |
| SCHEMBL12862672 | 0.77 | NLRP3 (0.41) | SMN1; SMN2KMT2AMEN1GAACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |
| US-4046763-A | INTERMEDIATE FOR ULTRAVIOLET LIGHT ABSORBERS | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |