Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | PRCP | P42785 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.41 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682895 | 0.85 | KCNH2 (0.57) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11684960 | 0.85 | OPRD1 (0.57) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11884181 | 0.85 | OPRD1 (0.57) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11681814 | 0.82 | OPRD1 (0.54) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11858736 | 0.82 | OPRD1 (0.54) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11684907 | 0.81 | SIGMAR1 (0.70) | OPRD1SIGMAR1PRCPOPRM1OPRK1 | |
| SCHEMBL11880458 | 0.81 | OPRD1 (0.53) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11368769 | 0.81 | OPRD1 (0.52) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11840739 | 0.80 | OPRD1 (0.51) | OPRD1KCNH2SIGMAR1PRCPOPRM1 | |
| SCHEMBL11851978 | 0.80 | KCNH2 (0.52) | OPRD1KCNH2SIGMAR1PRCPOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | claimed |
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |