Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684152 | 0.88 | TSHR (0.42) | TP53TSHRKMT2ARXFP1PNMT | |
| SCHEMBL11680182 | 0.88 | TSHR (0.38) | TP53TSHRKMT2ARXFP1PNMT | |
| 3-Chloroaniline SCHEMBL11684018 | 0.86 | ALDH1A1 (0.44) | TP53TSHRKMT2ARXFP1PNMT | |
| SCHEMBL11684625 | 0.83 | SENP3 (0.43) | TP53TSHRKMT2AHTR3EHTR3B | |
| Aniline SCHEMBL11683612 | 0.80 | PRMT1 (0.38) | TSHRKMT2ARXFP1CCR2NOS3 | |
| SCHEMBL11682158 | 0.76 | TSHR (0.46) | TP53TSHRCCR2 | |
| SCHEMBL11682698 | 0.75 | LMNA (0.33) | — | |
| SCHEMBL294676 | 0.74 | PNMT (0.54) | KMT2ARXFP1PNMTHTR3EHTR3B | |
| SCHEMBL29581044 | 0.74 | PNMT (0.54) | KMT2ARXFP1PNMTHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL28332854 | 0.72 | PNMT (0.52) | KMT2ARXFP1PNMTHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |