Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 12/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 12/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 12/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 12/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 12/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 12/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808822 | 0.86 | MAPT (0.44) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1039443 | 0.85 | ADRA1D (0.48) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1809065 | 0.85 | PTGS2 (0.49) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23665727 | 0.82 | PSEN1 (0.41) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11545414 | 0.82 | DDR1 (0.44) | MAPTMEN1SLC22A1USP2LMNA | |
| SCHEMBL2914223 | 0.82 | TRPV4 (0.39) | MAPTMEN1SLC22A1USP2LMNA | |
| SCHEMBL14395643 | 0.81 | DDR1 (0.38) | MAPTMEN1SLC22A1USP2LMNA | |
| SCHEMBL5957559 | 0.78 | CNR2 (0.40) | MAPTMEN1SLC22A1USP2LMNA | |
| SCHEMBL23665847 | 0.78 | PSEN1 (0.42) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11680272 | 0.76 | MEP1B (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057418-A | Sulfonylmethylamino-substituted benzoic acids and herbicidal method therewith | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |