Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686057 | 0.77 | PGR (0.51) | SMN1; SMN2POLBL3MBTL1RXFP1MEN1 | |
| SCHEMBL11685526 | 0.74 | PGR (0.51) | POLBL3MBTL1RXFP1MEN1KMT2A | |
| SCHEMBL11684709 | 0.73 | PGR (0.49) | SMN1; SMN2POLBL3MBTL1RXFP1MEN1 | |
| SCHEMBL8769337 | 0.69 | POLB (0.56) | SMN1; SMN2POLBL3MBTL1RXFP1MEN1 | |
| SCHEMBL11685529 | 0.68 | POLB (0.43) | SMN1; SMN2POLBL3MBTL1RXFP1MEN1 | |
| SCHEMBL6152252 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBL3MBTL1RXFP1MEN1 | |
| SCHEMBL5464725 | 0.66 | ALDH1A1 (0.58) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11742164 | 0.66 | CYP1A2 (0.50) | SMN1; SMN2POLBL3MBTL1RXFP1MEN1 | |
| SCHEMBL11686420 | 0.66 | ESR1 (0.46) | SMN1; SMN2KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL7551579 | 0.65 | HSD17B10 (0.43) | SMN1; SMN2POLBL3MBTL1RXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |