Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686582 | 0.89 | MEN1 (0.44) | TP53LMNAPOLBNPC1RAB9A | |
| SCHEMBL527094 | 0.83 | ALDH1A1 (0.46) | LMNAPOLBHDAC6NPC1RAB9A | |
| SCHEMBL11687255 | 0.83 | EPHX2 (0.46) | TP53LMNAPOLBNPC1RAB9A | |
| SCHEMBL135086 | 0.83 | LMNA (0.58) | TP53LMNAPOLB | |
| SCHEMBL11686667 | 0.81 | LMNA (0.59) | TP53LMNAPOLBPNPLA2HDAC6 | |
| SCHEMBL11684390 | 0.80 | LMNA (0.72) | TP53LMNAPOLB | |
| SCHEMBL11686660 | 0.80 | LMNA (0.55) | TP53LMNAPOLB | |
| SCHEMBL11683384 | 0.80 | LMNA (0.55) | TP53LMNAPOLBPNPLA2HDAC6 | |
| SCHEMBL11208625 | 0.79 | PPARA (0.53) | TP53PNPLA2HDAC6 | |
| SCHEMBL11176132 | 0.78 | TP53 (0.52) | TP53LMNAPOLBPNPLA2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013452-A | Urea derivatives and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3937726-A | UREA DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |