Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25471843 | 0.92 | ITGB3 (0.49) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| SCHEMBL1070435 | 0.88 | ITGB3 (0.46) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| SCHEMBL25188179 | 0.88 | ITGB3 (0.46) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| SCHEMBL1071712 | 0.87 | HDAC3 (0.44) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| SCHEMBL22290251 | 0.87 | HDAC3 (0.44) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11454643 | 0.87 | ITGB3 (0.46) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| SCHEMBL11862343 | 0.86 | CCR5 (0.55) | FPR2CCR5CA2 | |
| SCHEMBL11794176 | 0.86 | PPARG (0.57) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| SCHEMBL11860866 | 0.86 | PPARG (0.57) | ALOX15LDHAFPR2ALDH1A1KDM4E | |
| SCHEMBL8232221 | 0.86 | MME (0.49) | ALOX15LDHAFPR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065566-A | PRO-DRUG FORM OF L-DOPA, PARKINSON*S DISEASE | INTERX RESEARCH CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4035507-A | Novel, transient pro-drug forms of L-DOPA to treat Parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-3998799-A | FOR TREATMENT OF PARKINSON'S DISEASE | INTERX RESEARCH CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |