SCHEMBL11684357

SCHEMBL11684357

O=C1C(Cl)C(Cl)C(Cl)C1Cl

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.32
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRR1 P24046 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA6 Q16445 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11258035 0.67
SCHEMBL10781089 0.67 KDM4E (0.32) LMNA
SCHEMBL12315070 0.67
SCHEMBL6758482 0.64
SCHEMBL31263243 0.63 ATM (0.34) S100A4
SCHEMBL1163525 0.63
SCHEMBL7123367 0.61 LMNA (0.33) LMNACYP3A4GABRA1GABRB1GABRG2
SCHEMBL5115934 0.58
SCHEMBL5842299 0.56
SCHEMBL21443828 0.56 S100A4 (0.43) S100A4CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4060555-A DEACON CATALYST ALLIED CHEMICAL CORPORATION (US) 1977-11-29 US disclosed