Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038922 | 0.64 | — | — | |
| SCHEMBL11684357 | 0.61 | S100A4 (0.32) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| SCHEMBL8723350 | 0.55 | — | — | |
| SCHEMBL8674405 | 0.55 | — | — | |
| Lindane SCHEMBL9120917 | 0.54 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL8110265 | 0.54 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL472088 | 0.54 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Alpha-Hexachlorocyclohexane SCHEMBL140813 | 0.54 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL9242537 | 0.54 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL10795898 | 0.54 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030215859-A1 | DNA shuffling of monooxygenase genes for production of industrial chemicals | MAXYGEN, INC. | 2003-11-20 | — | — | US | disclosed |
| US-6605430-B1 | Genetic engineering to produce library of polynucleotides encoding polypeptides; screening, recovering | MAXYGEN, INC. | 2003-08-12 | — | — | US | disclosed |
| EP-1104459-A1 | DNA SHUFFLING OF MONOOXYGENASE GENES FOR PRODUCTION OF INDUSTRIAL CHEMICALS | Maxygen, Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009682-A1 | DNA SHUFFLING OF MONOOXYGENASE GENES FOR PRODUCTION OF INDUSTRIAL CHEMICALS | MAXYGEN, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| US-4602994-A | Removal of PCBs and other halogenated organic compounds from organic fluids | THE FRANKLIN INSTITUTE (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0140999-A1 | Removal of halogenated organic compounds from organic fluids | Calspan Corporation (US) | 1985-05-15 | — | — | EP | disclosed |
| EP-0107404-A1 | Removal of halogenated organic compounds from organic fluids | Calspan Corporation (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4417977-A | Removal of PCBS and other halogenated organic compounds from organic fluids | THE FRANKLIN INSTITUTE (US) | 1983-11-29 | — | — | US | disclosed |
| US-4053439-A | METAL SALT OF AROMATIC CARBOXYLATE | ARMSTRONG CORK COMPANY (US) | 1977-10-11 | — | — | US | disclosed |