SCHEMBL31263243

SCHEMBL31263243

O=C1C(Cl)C2C=CC(O2)C1Cl

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.34
S100A4 P26447 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19251729 0.69 ATM (0.33) ATM
SCHEMBL3654096 0.69 ATM (0.33) ATM
SCHEMBL15898403 0.69 ATM (0.33) ATM
SCHEMBL19277780 0.69 ATM (0.33) ATM
SCHEMBL17525226 0.69 ATM (0.33) ATM
SCHEMBL11684357 0.63 S100A4 (0.32) S100A4
SCHEMBL1105712 0.63 KDM4E (0.44) ATM
SCHEMBL18874109 0.63 ATM (0.42) ATM
SCHEMBL18022167 0.63 KDM4E (0.44) ATM
SCHEMBL11974005 0.63 KDM4E (0.44) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709719-A1 5-CYANO-1H-IMIDAZOLE-2-CARBOXAMIDE COMPOUNDS AS CSF1R INHIBITORS Modulo Bio, Inc. (US) 2026-03-18 EP disclosed
WO-2024254440-A1 5-CYANO-1H-IMIDAZOLE-2-CARBOXAMIDE COMPOUNDS AS CSF1R INHIBITORS MODULO BIO, INC. (US) 2024-12-12 WO disclosed