Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.69 |
| ▸ | SHBG | P04278 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.61 |
| ▸ | PGR | P06401 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128191 | 0.86 | SHBG (0.68) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| SCHEMBL11688675 | 0.85 | HIF1A (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| SCHEMBL11686670 | 0.85 | HIF1A (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| SCHEMBL9862493 | 0.84 | HSD17B10 (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| SCHEMBL9862485 | 0.84 | HSD17B10 (0.71) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| Cortodoxone SCHEMBL24900239 | 0.82 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| Cortodoxone SCHEMBL42590 | 0.82 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| Cortodoxone SCHEMBL14360590 | 0.82 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| Cortodoxone SCHEMBL13768127 | 0.82 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A | |
| Cortodoxone SCHEMBL17906542 | 0.82 | HSD17B10 (1.00) | HSD17B10SHBGSMN1; SMN2SERPINA6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012510-A | Novel methylene steroids | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-03-15 | — | — | US | disclosed |