Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685718 | 0.85 | MAPT (0.46) | HSD17B1HSD17B2ALDH1A1TSHRPGR | |
| SCHEMBL11685235 | 0.83 | KDM4E (0.42) | HSD17B1HSD17B2ALDH1A1TDP1NR1H3 | |
| SCHEMBL11689577 | 0.83 | KDM4E (0.55) | ALDH1A1TSHRNR1H3PGRKDM4E | |
| SCHEMBL11682666 | 0.81 | KDM4E (0.45) | HSD17B1HSD17B2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11683316 | 0.81 | ALDH1A1 (0.48) | HSD17B1HSD17B2ALDH1A1TSHRHSD17B10 | |
| Methane SCHEMBL11682364 | 0.80 | KDM4E (0.44) | HSD17B1HSD17B2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11348719 | 0.75 | ALDH1A1 (0.55) | HSD17B1HSD17B2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10348034 | 0.72 | NSD2 (0.54) | HSD17B1HSD17B2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11684564 | 0.72 | CA12 (0.49) | HSD17B1HSD17B2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL27740152 | 0.72 | PGR (0.63) | HSD17B1HSD17B2ALDH1A1TDP1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |