Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684642 | 0.83 | HSD17B1 (0.47) | KDM4EALDH1A1HSD17B1HSD17B2NR1H3 | |
| SCHEMBL11682345 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HSD17B1HSD17B2MCOLN3 | |
| SCHEMBL11689577 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1NR1H3PGRMCOLN3 | |
| SCHEMBL11685718 | 0.76 | MAPT (0.46) | KDM4EALDH1A1HSD17B1HSD17B2PGR | |
| SCHEMBL11683080 | 0.69 | LMNA (0.41) | KDM4EALDH1A1NR1H3LMNAMAPT | |
| SCHEMBL11518478 | 0.69 | CA1 (0.43) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL25920645 | 0.69 | HSD17B1 (0.49) | KDM4EHSD17B1HSD17B2PGRLMNA | |
| SCHEMBL30270588 | 0.69 | HSD17B1 (0.49) | KDM4EHSD17B1HSD17B2PGRLMNA | |
| SCHEMBL13577005 | 0.69 | PGR (0.49) | KDM4EALDH1A1HSD17B1HSD17B2PGR | |
| SCHEMBL11682961 | 0.68 | ESR1 (0.51) | KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |