SCHEMBL124524

SCHEMBL124524

OCc1cccc(Cc2cccc(CO)c2O)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.50
GABRB2 P47870 3/20 0.50
HSPA5 P11021 1/20 0.46
HSP90AA1 P07900 1/20 0.44
APOBEC3G Q9HC16 1/20 0.41
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.37
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
SHBG P04278 1/20 0.35
HMGB1 P09429 1/20 0.35
CXCL12 P48061 1/20 0.35
CALM1 P0DP23 1/20 0.35
ADAMTS4 O75173 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23486766 1.00 GABRA1 (0.50) GABRA1GABRB2HSPA5HSP90AA1APOBEC3G
SCHEMBL196227 0.92 GABRA1 (0.57) GABRA1GABRB2HSPA5APOBEC3GPDCD1
SCHEMBL25975547 0.89 GABRA1 (0.71) GABRA1GABRB2HSPA5HSP90AA1PDCD1
SCHEMBL11686142 0.89 HSPA5 (0.67) GABRA1GABRB2HSPA5LMNAKDM4E
SCHEMBL18462974 0.87 ALDH1A1 (0.50) GABRA1GABRB2HSPA5HSP90AA1PDCD1
SCHEMBL9418419 0.85 KDM4E (0.50) GABRA1GABRB2HSPA5HSP90AA1KDM4E
SCHEMBL28330365 0.84 BCL2 (0.52) TSHRCALM1
SCHEMBL17902715 0.83 SHBG (0.50) GABRA1GABRB2HSP90AA1KDM4ESHBG
SCHEMBL14289798 0.82 KDM4E (0.47) GABRA1GABRB2HSP90AA1KDM4ESHBG
SCHEMBL14272185 0.82 CALM1 (0.59) LMNAKDM4ETP53MAPTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0370595-B1 Binder compositions comprising low molecular weight poly(orthomethylolated)phenolic compound and novolac resin BORDEN INC (US) 1994-09-07 EP claimed
US-20230295407-A1 Thermoplastic Vulcanizate Compositions Containing Metallocene Multimodal Copolymer Rubber and Processes for Making Same EXXONMOBIL CHEMICAL PATENTS (US) 2023-09-21 US disclosed
US-20230193010-A1 Pipe Including a Polymethylpentene Thermoplastic Polymer CELANESE INT CORP (US) 2023-06-22 US disclosed
US-11674024-B2 Sequential, double elastomer vulcanization system, method and composition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-06-13 US disclosed
US-11028323-B2 Liquid crystal aligning agent containing crosslinking agent and polymer that has site having isocyanate group and/or blocked isocyanate group and site having photoreactivity, liquid crystal alignment film, and liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-06-08 US disclosed
US-10921650-B2 Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2021-02-16 US disclosed
US-20190023987-A1 LIQUID CRYSTAL ALIGNING AGENT CONTAINING CROSSLINKING AGENT AND POLYMER THAT HAS SITE HAVING ISOCYANATE GROUP AND/OR BLOCKED ISOCYANATE GROUP AND SITE HAVING PHOTOREACTIVITY, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-01-24 US disclosed
US-20190018289-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-01-17 US disclosed
US-20180072877-A1 THERMOPLASTIC ELASTOMER COMPOSITION, USE THEREOF, METHOD FOR PRODUCING SAME, ETHYLENE/a-OLEFIN/UNCONJUGATED POLYENE COPOLYMER AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2018-03-15 US disclosed
US-20180030219-A1 Method of Making Thermoplastic Vulcanizates and Thermoplastic Vulcanizates Made Therefrom CELANESE INTERNATIONAL CORPORATION 2018-02-01 US disclosed
US-20070135576-A1 Thermoplastic elastomer composition RIKEN TECHNOS CORPORATION (JP) 2007-06-14 US disclosed
US-20070134497-A1 Thermoplastic vulcanizate adhesive compositions CELANESE INTERNATIONAL CORPORATION 2007-06-14 US disclosed
US-20070055020-A1 Elastomeric compositions containing fluoropolymer blends FREUDENBERG-NOK GENERAL PARTNERSHIP (US) 2007-03-08 US disclosed
US-20070004862-A1 Base resistant FKM-TPV elastomers FREUDENBERG-NOK GENERAL PARTNERSHIP (US) 2007-01-04 US disclosed
US-20070000926-A1 Thermoplastic vulcanizates and sealing devices made therewith CELANESE INTERNATIONAL CORPORATION 2007-01-04 US disclosed
EP-0106156-B1 LIGHT-SENSITIVE COMPOSITION HOECHST CELANESE CORPORATION (US) 1988-12-21 EP disclosed
EP-0106156-A2 Light-sensitive composition HOECHST CELANESE CORPORATION (US) 1984-04-25 EP disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed
US-4146576-A MANUFACTURE OF CARBON FIBRES COAL INDUSTRY (PATENTS) LIMITED (GB) 1979-03-27 US disclosed
US-4022942-A NOVOLAKS OR B-STAGE RESINS MONSANTO COMPANY (US) 1977-05-10 US disclosed