Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381727 | 0.81 | TSHR (0.58) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL1831719 | 0.81 | TSHR (0.58) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL7647641 | 0.77 | TSHR (0.52) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| SCHEMBL1500477 | 0.75 | TSHR (0.58) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL2547243 | 0.75 | CYP1A2 (0.65) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL151981 | 0.73 | TSHR (0.65) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL42163 | 0.73 | KCNN4 (0.47) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL4269900 | 0.73 | KCNN4 (0.47) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL2335365 | 0.73 | KCNN4 (0.47) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 | |
| SCHEMBL10940043 | 0.73 | TSHR (0.65) | TSHRCYP1A2KCNN4ALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049797-A | 1-PHENOXY-2-HYDROXY-3-AMINO-PROPANE-SUGAR COMPOUND | CIBA-GEIGY CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-3978041-A | CARDIAC INSUFFICIENCY | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |