Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444515 | 0.84 | TSHR (0.48) | TSHRCA1CA2CA5ACA9 | |
| SCHEMBL2335365 | 0.79 | KCNN4 (0.47) | KCNN4ALDH1A1TSHRCYP1A2PTPN1 | |
| SCHEMBL4269900 | 0.79 | KCNN4 (0.47) | KCNN4ALDH1A1TSHRCYP1A2PTPN1 | |
| SCHEMBL2462232 | 0.76 | KIF11 (0.36) | KCNN4ALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL10827620 | 0.76 | KCNN4 (0.45) | KCNN4ALDH1A1TSHRCYP1A2PTPN1 | |
| SCHEMBL207978 | 0.73 | MAPK1 (0.50) | KCNN4ALDH1A1TSHRCYP1A2MAPK1 | |
| SCHEMBL240161 | 0.73 | MAPK1 (0.50) | KCNN4ALDH1A1TSHRCYP1A2MAPK1 | |
| SCHEMBL11686299 | 0.73 | TSHR (0.58) | KCNN4ALDH1A1TSHRCYP1A2PTPN1 | |
| SCHEMBL424619 | 0.73 | TSHR (0.58) | KCNN4ALDH1A1TSHRCYP1A2PTPN1 | |
| SCHEMBL7381727 | 0.73 | TSHR (0.58) | KCNN4ALDH1A1TSHRCYP1A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1094 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317970-A | Synthesis of 2' acetyl-ester protected nucleosides | 兆维生物科技公司 | 2024-07-09 | — | — | CN | claimed |
| CN-115650827-B | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2024-03-15 | — | — | CN | claimed |
| WO-2023179773-A1 | BICYCLIC HETEROCYCLES AND THEIR LIGANDS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | HANSOH BIO LLC (US) | 2023-09-28 | — | — | WO | claimed |
| CN-106459021-B | Compositions and methods for treating neurodegenerative diseases | 阿泽范药品公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115650827-A | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115651043-A | Preparation method of anthracycline derivative | 戊言医药科技（上海）有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-113613730-A | Quinoline carboxamide derivative and process for producing intermediate for producing same | 株式会社益力多本社 | 2021-11-05 | — | — | CN | claimed |
| CN-113429307-A | Preparation method and application of stable isotope labeled glutamic acid and glutamic acid derivative | 深圳鼎邦生物科技有限公司 | 2021-09-24 | — | — | CN | claimed |
| US-10953001-B2 | Methods for treating post traumatic stress disorder | AZEVAN PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | claimed |
| EP-3351104-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF INTERMITTENT EXPLOSIVE DISORDER | AZEVAN PHARMACEUTICALS INC (US) | 2020-12-09 | — | — | EP | claimed |
| US-4405530-A | Process for preparing fluorinated amino-nitriles | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-09-20 | — | — | US | claimed |
| US-4385177-A | Cephalosporins having a carbamoylalkoxyiminoarylacetamido group at 7-position | GLAXO LABORATORIES, LTD. (GB) | 1983-05-24 | — | — | US | claimed |
| EP-0074861-A1 | Aminocyclopentane esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | claimed |
| EP-0002774-B1 | PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | claimed |
| US-4179451-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATOR, ANTICONVULSANTS OR ANTIMICROBIAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | claimed |
| US-4143037-A | THIOHYDRAZOAZETIDINONES | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-03-06 | — | — | US | claimed |
| US-4064173-A | 9,10-Seco-steroids | HOFFMANN-LA ROCHE, INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-4045490-A | 9,10-Seco-steroid preparation | HOFFMANN-LA ROCHE INC. (US) | 1977-08-30 | — | — | US | claimed |
| US-4036835-A | Process for preparing cephalosporins | SOCIETA' FARMACEUTICI ITALIA (IT) | 1977-07-19 | — | — | US | claimed |
| US-4012381-A | Process for preparing cephalosporins and intermediates | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1977-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953001-B2 | Methods for treating post traumatic stress disorder | GPX4, CRH, TXN | KCNN4 2383/4885ALDH1A1 1136/4885TSHR 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.