Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685252 | 0.83 | TDP1 (0.54) | CYP3A4TRPA1MAPK1TDP1PPARG | |
| SCHEMBL11684121 | 0.78 | PPARG (0.40) | CYP3A4TRPA1MAPK1TDP1PPARG | |
| SCHEMBL9918953 | 0.78 | CYP3A4 (0.45) | CYP3A4TRPA1MAPK1TDP1KDM4E | |
| SCHEMBL5825529 | 0.73 | SMN1; SMN2 (0.54) | MAPK1KDM4ETSHRALDH1A1MAPT | |
| SCHEMBL17874342 | 0.72 | FDPS (0.49) | CYP3A4TRPA1TDP1ALDH1A1MAPT | |
| SCHEMBL4163589 | 0.72 | TRPA1 (0.49) | CYP3A4TRPA1MAPK1TDP1KDM4E | |
| SCHEMBL9859232 | 0.72 | CYP3A4 (0.49) | CYP3A4TRPA1MAPK1TDP1PPARG | |
| SCHEMBL9720455 | 0.71 | CYP3A4 (0.50) | CYP3A4TRPA1MAPK1TDP1MAPT | |
| SCHEMBL9576009 | 0.71 | CYP3A4 (0.51) | CYP3A4TRPA1MAPK1TDP1KDM4E | |
| SCHEMBL58809 | 0.70 | CYP3A4 (0.70) | CYP3A4TRPA1MAPK1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013452-A | Urea derivatives and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3937726-A | UREA DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |