Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865940 | 0.97 | MGLL (0.42) | MGLL | |
| SCHEMBL16919356 | 0.79 | NPC1 (0.48) | MGLL | |
| SCHEMBL1169021 | 0.78 | HCRTR1 (0.40) | MGLL | |
| SCHEMBL20226254 | 0.78 | MGLL (0.50) | MGLL | |
| SCHEMBL20544861 | 0.76 | CA12 (0.41) | MGLL | |
| SCHEMBL20226263 | 0.76 | ESR1 (0.46) | MGLL | |
| SCHEMBL20226252 | 0.76 | MGLL (0.58) | MGLL | |
| SCHEMBL1546308 | 0.75 | MGLL (0.52) | MGLL | |
| SCHEMBL12979663 | 0.75 | NPC1 (0.40) | — | |
| SCHEMBL1546349 | 0.75 | KMT2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772197-B2 | Compositions for chemical and biological defense | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772197-B2 | Compositions for chemical and biological defense | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-07-08 | — | — | US | disclosed |
| US-20110027869-A1 | Compositions for Chemical and Biological Defense | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110027869-A1 | Compositions for Chemical and Biological Defense | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-02-03 | — | — | US | disclosed |
| WO-2009055128-A2 | COMPOSITIONS FOR CHEMICAL AND BIOLOGICAL DEFENSE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110027869-A1 | Compositions for Chemical and Biological Defense | LPO, MPO, GPX4 | MGLL 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.