Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24400471 | 0.92 | TYMS (0.44) | TYMSCYP1A2TDP1CYP2A6MEN1 | |
| SCHEMBL4105237 | 0.78 | CYP2A6 (0.59) | TYMSCYP1A2TDP1CYP2A6MEN1 | |
| SCHEMBL31362060 | 0.78 | CYP2A6 (0.59) | TYMSCYP1A2TDP1CYP2A6MEN1 | |
| SCHEMBL29587339 | 0.77 | MEN1 (0.48) | CYP1A2TDP1CYP2A6MEN1KMT2A | |
| SCHEMBL5276864 | 0.77 | MEN1 (0.48) | CYP1A2TDP1CYP2A6MEN1KMT2A | |
| SCHEMBL30366723 | 0.74 | CYP1A2 (0.67) | TYMSCYP1A2TDP1CYP2A6KMT2A | |
| SCHEMBL20356035 | 0.74 | CYP1A2 (0.67) | TYMSCYP1A2TDP1CYP2A6KMT2A | |
| SCHEMBL1254074 | 0.74 | CYP2A6 (0.59) | CYP1A2TDP1CYP2A6MEN1KMT2A | |
| SCHEMBL14485908 | 0.73 | ERN1 (0.44) | CYP1A2TDP1MEN1KMT2ALMNA | |
| SCHEMBL549009 | 0.73 | LMNA (0.57) | CYP1A2TDP1CYP2A6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042624-A | Antidepressant 2-[(substituted-1-naphthylmethyl)amino]-1-phenylpropanols | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-08-16 | — | — | US | disclosed |