Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362060 | 1.00 | CYP2A6 (0.59) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL1254074 | 0.86 | CYP2A6 (0.59) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL4245330 | 0.85 | MEN1 (0.61) | CYP2A6MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL28120060 | 0.79 | ALDH1A1 (0.43) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL24400471 | 0.78 | TYMS (0.44) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL11690201 | 0.78 | TYMS (0.44) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL3267169 | 0.78 | CYP2A6 (0.48) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL3628055 | 0.77 | ALDH1A1 (0.60) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL2468811 | 0.77 | CYP1A2 (1.00) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL29629127 | 0.77 | CYP1A2 (1.00) | CYP2A6CYP1A2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848359-B1 | METHOD FOR PRODUCING TRIFLUOROPYRUVATE FLUORIDE DIMER, AND METHOD FOR PRODUCING PERFLUORO(2,4-DIMETHYL-2-FLUOROFORMYL-1,3-DIOXOLANE) | TOSOH CORP (JP) | 2024-06-12 | — | — | EP | disclosed |
| US-20240067645-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | LG CHEM, LTD. (KR) | 2024-02-29 | — | — | US | disclosed |
| EP-4249489-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | Lg Chem, Ltd. (KR) | 2023-09-27 | — | — | EP | disclosed |
| CN-116615199-A | Heterocyclic compounds as diacylglycerol kinase inhibitors and uses thereof | 株式会社LG化学 | 2023-08-18 | — | — | CN | disclosed |
| US-11555024-B2 | Aldehyde adduct of hexafluoropropylene oxide, method of manufacturing trifluoropyruvyl fluoride dimer and method of manufacturing perfluoro(2,4-dimethyl-2-fluoroformyl-1,3-dioxolane) | TOSOH CORPORATION (JP) | 2023-01-17 | — | — | US | disclosed |
| WO-2022114812-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2022-06-02 | — | — | WO | disclosed |
| US-20210214332-A1 | Aldehyde adduct of hexafluoropropylene oxide, method of manufacturing trifluoropyruvyl fluoride dimer and method of manufacturing perfluoro(2,4-dimethyl-2-fluoroformyl-1,3-dioxolane) | TOSOH CORPORATION (JP) | 2021-07-15 | — | — | US | disclosed |
| EP-3848359-A1 | ALDEHYDE ADDUCT TO HEXAFLUOROPROPYLENE OXIDE, METHOD FOR PRODUCING TRIFLUOROPYRUVATE FLUORIDE DIMER, AND METHOD FOR PRODUCING PERFLUORO(2,4-DIMETHYL-2-FLUOROFORMYL-1,3-DIOXOLANE) | Tosoh Corporation (JP) | 2021-07-14 | — | — | EP | disclosed |
| CN-111499667-A | Method for synthesizing trivalent tetraarylferriporphyrin from pyrrole, aromatic aldehyde and ferrous salt | 沅江华龙催化科技有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| CN-101155817-A | Dihydroimidazothiazole derivatives | PROSIDION LTD (GB) | 2008-04-02 | — | — | CN | disclosed |
| EP-0746320-B1 | HIV PROTEASE INHIBITORS AND INTERMEDIATES | LILLY CO ELI (US) | 2001-01-31 | — | — | EP | disclosed |
| US-5734057-A | VIRICIDE | ELI LILLY AND COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0746320-A4 | HIV PROTEASE INHIBITORS AND INTERMEDIATES | LILLY CO ELI (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0746320-A1 | HIV PROTEASE INHIBITORS AND INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995020965-A1 | HIV PROTEASE INHIBITORS AND INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1995-08-10 | — | — | WO | disclosed |
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | CYP2A6 447/4885CYP1A2 137/4885MEN1 2481/4885 |
| US-11555024-B2 | Aldehyde adduct of hexafluoropropylene oxide, method of manufacturing trifluoropyruvyl fluoride dimer and method of manufacturing perfluoro(2,4-dimethyl-2-fluoroformyl-1,3-dioxolane) | PFAS, PFDN2, AFF2 | CYP2A6 950/4885CYP1A2 271/4885MEN1 4247/4885 |
| US-20210214332-A1 | Aldehyde adduct of hexafluoropropylene oxide, method of manufacturing trifluoropyruvyl fluoride dimer and method of manufacturing perfluoro(2,4-dimethyl-2-fluoroformyl-1,3-dioxolane) | PFAS, PFDN2, AFF2 | CYP2A6 950/4885CYP1A2 271/4885MEN1 4247/4885 |
| US-20240067645-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | DGKA, DGKB, DGKK | CYP2A6 1877/4885CYP1A2 1258/4885MEN1 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.