Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375140 | 0.84 | ALDH1A1 (0.49) | KIF18AGPR35VCAM1TSHRALDH1A1 | |
| SCHEMBL3696313 | 0.84 | GPR35 (0.47) | GPR35VCAM1TSHRALDH1A1TDP1 | |
| SCHEMBL29135017 | 0.82 | GPR35 (0.41) | KIF18AGPR35VCAM1TSHRALDH1A1 | |
| SCHEMBL11690992 | 0.82 | KIF18A (0.42) | KIF18AVCAM1TSHRALDH1A1TDP1 | |
| SCHEMBL9452603 | 0.80 | TSHR (0.59) | GPR35VCAM1TSHRALDH1A1TDP1 | |
| SCHEMBL12263626 | 0.78 | TRPV4 (0.41) | KIF18AVCAM1TSHRALDH1A1TDP1 | |
| SCHEMBL135289 | 0.78 | CASP6 (0.47) | GPR35VCAM1TSHRALDH1A1TDP1 | |
| SCHEMBL2062571 | 0.78 | MAPK1 (0.58) | KIF18AVCAM1TSHRALDH1A1MAPK1 | |
| SCHEMBL1052777 | 0.78 | KIF18A (0.64) | KIF18AVCAM1TSHRALDH1A1MAPK1 | |
| SCHEMBL30821752 | 0.78 | KIF18A (0.64) | KIF18AVCAM1TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |