Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11692045 | 0.99 | SIGMAR1 (0.42) | SIGMAR1NR3C1PGRNR3C2CTNNB1 | |
| SCHEMBL2827348 | 0.88 | SIGMAR1 (0.46) | SIGMAR1NR3C1PGRNR3C2KMT2A | |
| SCHEMBL7058293 | 0.83 | KMT2A (0.43) | SIGMAR1NR3C1PGRNR3C2CTNNB1 | |
| SCHEMBL18896255 | 0.79 | TDP1 (0.45) | KMT2AL3MBTL1MEN1MAPTKCNH2 | |
| SCHEMBL23861793 | 0.77 | HDAC8 (0.44) | — | |
| SCHEMBL21499101 | 0.77 | HDAC8 (0.44) | — | |
| SCHEMBL4688472 | 0.77 | HDAC8 (0.44) | — | |
| SCHEMBL20987622 | 0.77 | HDAC8 (0.44) | — | |
| SCHEMBL25124425 | 0.77 | ENPP2 (0.43) | KMT2AMEN1MAPTTLR8TLR7 | |
| SCHEMBL19271855 | 0.77 | HDAC8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049393-A | DISAZO DYE DISSOLVED IN GASOLINE, KEROSENE, FUEL OILS, LUBRICANTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-09-20 | — | — | US | disclosed |
| US-4009008-A | DISAZO DYE | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-02-22 | — | — | US | disclosed |