SCHEMBL2827348

SCHEMBL2827348

CCCCCCCCc1ccc(NC(CCCCCC)Cc2cccc3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.46
KMT2A Q03164 3/20 0.41
IDE P14735 1/20 0.41
UBE2N P61088 1/20 0.41
SPHK1 Q9NYA1 5/20 0.38
HTR2A P28223 1/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SPHK2 Q9NRA0 1/20 0.37
NR3C1 P04150 1/20 0.37
PGR P06401 1/20 0.37
NR3C2 P08235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11692045 0.89 SIGMAR1 (0.42) SIGMAR1KMT2AIDEUBE2NKDM4E
SCHEMBL11693282 0.88 SIGMAR1 (0.43) SIGMAR1KMT2AIDEUBE2NKDM4E
SCHEMBL7058293 0.80 KMT2A (0.43) SIGMAR1KMT2AIDEUBE2NKDM4E
SCHEMBL28900394 0.74 KDM4E (0.44) SIGMAR1KMT2AKDM4EL3MBTL1
SCHEMBL9859804 0.73 KDM4E (0.46) SIGMAR1KMT2AKDM4EL3MBTL1
SCHEMBL294932 0.72 ALDH1A1 (0.54) KMT2AHTR2AKDM4EL3MBTL1
SCHEMBL1705432 0.72 ALDH1A1 (0.54) KMT2AHTR2AKDM4EL3MBTL1
SCHEMBL110264 0.72 ALDH1A1 (0.54) KMT2AHTR2AKDM4EL3MBTL1
SCHEMBL293780 0.72 ALDH1A1 (0.54) KMT2AHTR2AKDM4EL3MBTL1
SCHEMBL283950 0.72 LIPG (0.55) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1121404-B1 HIGH PERFORMANCE LUBRICATING OILS EXXONMOBIL OIL CORP (US) 2016-02-03 EP disclosed
EP-2021440-B1 LUBRICATING OIL COMPOSITION SHELL INT RESEARCH (NL) 2015-07-01 EP disclosed
US-8476205-B2 Chromium HVI-PAO bi-modal lubricant compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-07-02 US disclosed
US-8399390-B2 HVI-PAO in industrial lubricant and grease compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-19 US disclosed
US-8273694-B2 Synthetic compositions obtained from algae Brown, Jeffrey A (US) 2012-09-25 US disclosed
EP-2344581-B1 IMPROVED HVI-PAO BI-MODAL LUBRICANT COMPOSITIONS EXXONMOBIL RES & ENG CO (US) 2012-06-27 EP disclosed
EP-2194114-A2 Lubricating composition Shell Internationale Research Maatschappij B.V. (NL) 2010-06-09 EP disclosed
US-20100120643-A1 Synthetic compositions obtained from algae YUTOMI, INC. 2010-05-13 US disclosed
US-20100105589-A1 Chromium HVI-PAO bi-modal lubricant compositions EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2010-04-29 US disclosed
EP-2159275-A2 Lubricating composition Shell Internationale Research Maatschappij B.V. (NL) 2010-03-03 EP disclosed
US-5562864-A OIL WITH ONE CARBOXY DERIVATIVE FORMED BY ACYLATION OF SUCCINIC ACID AND A MIXTURE OF OVERBASED SALT OF CARBOXYLIC ACID, OR ACID WITH SULFONIC ACID WITH MAGNESIUM OR CALCIUM COMPOUNDS THE LUBRIZOL CORPORATION (US) 1996-10-08 US disclosed
EP-0712834-A1 High oleic polyol esters, compositions and lubricants functional fluids and greases containing the same THE LUBRIZOL CORPORATION (US) 1996-05-22 EP disclosed
US-5490945-A OIL CONTAINING CARBOXYLIC MODIFIED POLYOLEFIN THE LUBRIZOL CORPORATION (US) 1996-02-13 US disclosed
EP-0535221-B1 LUBRICATING COMPOSITIONS LUBRIZOL CORP (US) 1996-01-31 EP disclosed
US-5486300-A Lubricating compositions THE LUBRIZOL CORPORATION (US) 1996-01-23 US disclosed
EP-0678569-A2 Lubricating compositions with improved oxidation resistance containing a dispersant and an antioxidant THE LUBRIZOL CORPORATION (US) 1995-10-25 EP disclosed
EP-0471071-B1 HIGH TEMPERATURE FUNCTIONAL FLUIDS LUBRIZOL CORP (US) 1995-08-30 EP disclosed
EP-0596048-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1994-05-11 EP disclosed
WO-1993023504-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1993-11-25 WO disclosed
WO-1991013133-A2 HIGH TEMPERATURE FUNCTIONAL FLUIDS THE LUBRIZOL CORPORATION (US) 1991-09-05 WO disclosed