Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11692045 | 0.85 | SIGMAR1 (0.42) | KMT2AKDM4EL3MBTL1NR3C1PGR | |
| SCHEMBL11693282 | 0.83 | SIGMAR1 (0.43) | KMT2AKDM4EL3MBTL1NR3C1PGR | |
| SCHEMBL28900394 | 0.82 | KDM4E (0.44) | KMT2AKDM4EL3MBTL1SIGMAR1HDAC1 | |
| SCHEMBL31332073 | 0.82 | NR3C1 (0.54) | KMT2ANR3C1PGRNR3C2SIGMAR1 | |
| SCHEMBL16174128 | 0.82 | NR3C1 (0.54) | KMT2ANR3C1PGRNR3C2SIGMAR1 | |
| SCHEMBL9859804 | 0.81 | KDM4E (0.46) | KMT2AKDM4EL3MBTL1SIGMAR1CTNNB1 | |
| SCHEMBL2827348 | 0.80 | SIGMAR1 (0.46) | KMT2AKDM4EL3MBTL1NR3C1PGR | |
| SCHEMBL9493810 | 0.79 | KDM4E (0.45) | KMT2AKDM4EL3MBTL1SIGMAR1CTNNB1 | |
| SCHEMBL6617420 | 0.79 | KDM4E (0.45) | KMT2AKDM4EL3MBTL1SIGMAR1CTNNB1 | |
| SCHEMBL9844481 | 0.79 | KDM4E (0.45) | KMT2AKDM4EL3MBTL1SIGMAR1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673801-B1 | TREATING MULTIPLE SCLEROSIS OR RHEUMATOID ARTHRITIS | PFIZER INC. | 2004-01-06 | — | — | US | disclosed |