Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.73 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22562994 | 0.93 | ALDH1A1 (0.63) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL6847300 | 0.89 | ALDH1A1 (0.59) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL420424 | 0.88 | ALDH1A1 (0.68) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL23890201 | 0.88 | ALDH1A1 (0.58) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL11696300 | 0.87 | ALDH3A1 (0.56) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL4003205 | 0.86 | ALDH1A1 (0.66) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL10612062 | 0.86 | ALDH1A1 (0.66) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL23890185 | 0.85 | ALDH1A1 (0.54) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL10942535 | 0.85 | ALDH1A1 (0.83) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 | |
| SCHEMBL9875023 | 0.85 | ALDH1A3 (0.63) | ALDH3A1ALDH1A1ALDH1A3CYP2A6CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9504660-B2 | Retinaldehyde mimetics and inhibitors of retinaldehyde dehydrogenase I in the treatment of disorders | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2016-11-29 | — | — | US | claimed |
| US-20140378530-A1 | RETINALDEHYDE MIMETICS AND INHIBITORS OF RETINALDEHYDE DEHYDROGENASE I IN THE TREATMENT OF DISORDERS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2014-12-25 | — | — | US | claimed |
| EP-2809309-A1 | RETINALDEHYDE MIMETICS AND INHIBITORS OF RETINALDEHYDE DEHYDROGENASE I IN THE TREATMENT OF DISORDERS | The Brigham and Women's Hospital, Inc. (US) | 2014-12-10 | — | — | EP | claimed |
| WO-2013116721-A1 | RETINALDEHYDE MIMETICS AND INHIBITORS OF RETINALDEHYDE DEHYDROGENASE I IN THE TREATMENT OF DISORDERS | THE BRIGHAM AND WOMEN'S HOSPTIAL, INC. (US) | 2013-08-08 | — | — | WO | claimed |
| US-20100047433-A1 | Polymer for detecting fingerprint, method of producing the same, composition for detecting fingerprint and method of detecting fingerprint using the same | TOAGOSEI CO., LTD (JP) | 2010-02-25 | — | — | US | claimed |
| EP-1434557-B1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KGAA (DE) | 2005-11-09 | — | — | EP | claimed |
| EP-1139990-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2004-05-06 | — | — | EP | claimed |
| US-4582903-A | Synthesis of unsaturated hydantoins with an inexpensive catalyst | STAUFFER CHEMICAL COMPANY (US) | 1986-04-15 | — | — | US | claimed |
| CN-119192004-A | Anti-oxidation polymerization-inhibition polymerizable diphenyl ketone photoinitiator and preparation method and application thereof | 北京化工大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-116854713-A | Fluoroboron dipyrrole type photothermal nanomaterial as well as synthesis method and application thereof | 湖北大学 | 2023-10-10 | — | — | CN | disclosed |
| US-11702398-B2 | Photoresponsive low-molecular weight material, adhesive, toner, and image forming method | Konica Minolta, Inc. (JP) | 2023-07-18 | — | — | US | disclosed |
| CN-113754610-A | Fluorescent probe and method for detecting DNA G-quadruplex in living cell mitochondria | 中国科学院化学研究所 | 2021-12-07 | — | — | CN | disclosed |
| EP-3632420-A1 | TREATMENT OF FIBROSIS | The University Of Birmingham (GB) | 2020-04-08 | — | — | EP | disclosed |
| US-9937133-B2 | Treatment of fibrosis | UCL BUSINESS PLC (GB) | 2018-04-10 | — | — | US | disclosed |
| US-4254035-A | BY REACTING GLYCINE AND AN AROMATIC ALDEHYDE IN THE PRESENCE OF ACETIC ANHYDRIDE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-03-03 | — | — | US | disclosed |
| EP-0022521-A1 | Preparation of cationic triaryl methane dyestuffs | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4002616-A | POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |
| US-3962220-A | ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962221-A | CONDENSATION, REDUCTION, OXIDATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378530-A1 | RETINALDEHYDE MIMETICS AND INHIBITORS OF RETINALDEHYDE DEHYDROGENASE I IN THE TREATMENT OF DISORDERS | ALDH1A2, ALDH1A3, LRAT | ALDH3A1 6/4885ALDH1A1 10/4885ALDH1A3 2/4885 |
| US-11702398-B2 | Photoresponsive low-molecular weight material, adhesive, toner, and image forming method | ICAM1, CDH1, ACTR5 | ALDH3A1 2584/4885ALDH1A1 2548/4885ALDH1A3 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.