SCHEMBL11697237

SCHEMBL11697237

CCOC(C)Oc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.55
TSHR P16473 1/20 0.44
PPARG P37231 4/20 0.43
PPARA Q07869 4/20 0.43
PPARD Q03181 2/20 0.43
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
CRHBP P24387 1/20 0.41
RAB9A P51151 1/20 0.41
CRHR2 Q13324 1/20 0.41
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41
MAOA P21397 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
NPY5R Q15761 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL997422 0.92 LMNA (0.46) LTA4HTSHRMAOALMNA
SCHEMBL3852488 0.86 LMNA (0.52) LTA4HTSHRPPARALMNA
SCHEMBL11695011 0.86 LTA4H (0.53) LTA4HTSHRPPARGPPARAPPARD
SCHEMBL4061902 0.85 CYP1A2 (0.51) PPARGPPARANPC1HPGDRAB9A
SCHEMBL11696544 0.84 LTA4H (0.61) LTA4HTSHRPPARGPPARAPPARD
SCHEMBL279167 0.82 L3MBTL1 (0.38) LTA4HPPARGPPARACRHBPCRHR2
SCHEMBL279565 0.82 L3MBTL1 (0.38) LTA4HPPARGPPARACRHBPCRHR2
SCHEMBL11657117 0.81 LTA4H (0.43) LTA4HTSHRPPARGPPARA
SCHEMBL27224303 0.81 RELA (0.59) PPARGPPARANPC1HPGDRAB9A
SCHEMBL4059616 0.80 LMNA (0.46) PPARGPPARAMAOALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4058627-A INSECTICIDE, MITICIDE CIBA-GEIGY CORPORATION (US) 1977-11-15 US claimed