Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684461 | 0.86 | KDM4E (0.41) | SHBGGABRA1GABRB2ALOX15ALOX12 | |
| SCHEMBL11694876 | 0.85 | SHBG (0.39) | SHBGGABRA1GABRB2DHFRALOX15 | |
| SCHEMBL10992586 | 0.82 | SHBG (0.37) | SHBGGABRA1GABRB2DHFRHSPA5 | |
| SCHEMBL4057921 | 0.81 | GABRA1 (0.56) | SHBGGABRA1GABRB2DHFRALOX15 | |
| SCHEMBL11682130 | 0.80 | GABRA1 (0.32) | GABRA1GABRB2ALOX15ALOX12 | |
| SCHEMBL11695330 | 0.79 | ACE2 (0.38) | SHBGFFAR1 | |
| SCHEMBL11682214 | 0.78 | ALOX15 (0.47) | GABRA1GABRB2DHFRALOX15ALOX12 | |
| SCHEMBL9110427 | 0.77 | ALOX5 (0.36) | ALOX15ALOX12HCAR2FFAR1GAA | |
| SCHEMBL11682547 | 0.77 | POLB (0.40) | GABRA1GABRB2DHFRALOX15ALOX12 | |
| SCHEMBL11692144 | 0.76 | SHBG (0.38) | SHBGGABRA1GABRB2DHFRHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020113-A | 4,4'-Methylenebis(2,6-diisobutylphenol) | THE QUAKER OATS COMPANY (US) | 1977-04-26 | — | — | US | disclosed |