Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28608879 | 0.91 | ALDH1A1 (0.48) | ALDH1A1SRD5A2HPGDSMN1; SMN2LMNA | |
| Benzophenone SCHEMBL27777844 | 0.84 | ALDH1A1 (0.78) | ALDH1A1SRD5A2HPGDSMN1; SMN2LMNA | |
| SCHEMBL29967256 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SRD5A2HPGDSMN1; SMN2LMNA | |
| SCHEMBL15001700 | 0.82 | KMT2A (0.65) | ALDH1A1HPGDSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL9066312 | 0.81 | ALDH1A1 (0.93) | ALDH1A1SRD5A2HPGDLMNAL3MBTL1 | |
| SCHEMBL314267 | 0.81 | ALDH1A1 (0.93) | ALDH1A1SRD5A2HPGDLMNAL3MBTL1 | |
| SCHEMBL2859236 | 0.80 | ALDH1A1 (0.64) | ALDH1A1SRD5A2HPGDSMN1; SMN2LMNA | |
| SCHEMBL315097 | 0.79 | TSHR (0.60) | ALDH1A1SRD5A2SMN1; SMN2TP53ALOX15 | |
| SCHEMBL10022962 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SRD5A2HPGDSMN1; SMN2LMNA | |
| SCHEMBL50522 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SRD5A2HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051168-A | TO FORM FLUOROALKYL AROMATIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-27 | — | — | US | disclosed |