SCHEMBL29967256

SCHEMBL29967256

CC(F)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
SRD5A2 P31213 1/20 0.54
SMN1; SMN2 Q16637 5/20 0.51
HPGD P15428 5/20 0.51
PTGS1 P23219 3/20 0.51
PTGS2 P35354 3/20 0.51
LMNA P02545 3/20 0.51
RAB9A P51151 3/20 0.51
MAPT P10636 2/20 0.51
CXCR1 P25024 2/20 0.51
CXCR2 P25025 2/20 0.51
ELANE P08246 2/20 0.51
HTT P42858 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
RECQL P46063 1/20 0.51
KDM4E B2RXH2 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAPK1 P28482 1/20 0.51
PMP22 Q01453 1/20 0.51
SLC22A6 Q4U2R8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10022962 0.83 ALDH1A1 (0.61) ALDH1A1SRD5A2SMN1; SMN2HPGDPTGS1
SCHEMBL11698993 0.83 ALDH1A1 (0.61) ALDH1A1SRD5A2SMN1; SMN2HPGDPTGS1
SCHEMBL50522 0.83 ALDH1A1 (0.61) ALDH1A1SRD5A2SMN1; SMN2HPGDPTGS1
SCHEMBL17816171 0.83 MAPT (0.70) ALDH1A1SMN1; SMN2HPGDPTGS1PTGS2
SCHEMBL28587552 0.82 ALDH1A1 (0.58) ALDH1A1SRD5A2SMN1; SMN2HPGDPTGS1
SCHEMBL5211118 0.81 TSHR (0.55) ALDH1A1SRD5A2SMN1; SMN2HPGDKMT2A
SCHEMBL465683 0.81 ALDH1A1 (0.52) ALDH1A1SRD5A2SMN1; SMN2HPGDPTGS1
Bicarbonate SCHEMBL28309384 0.81 CYP2D6 (0.48) PTGS2LMNAMAPK1HIF1ANPC1
Benzophenone SCHEMBL27777844 0.80 ALDH1A1 (0.78) ALDH1A1SRD5A2SMN1; SMN2HPGDLMNA
SCHEMBL677887 0.80 ALDH1A1 (0.56) ALDH1A1SRD5A2SMN1; SMN2HPGDPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141138-B Method for constructing fluoride by decarboxylation of alkyl carboxylic acid 中山大学 2023-11-28 CN disclosed
CN-115141138-A Method for constructing fluoride by decarboxylation of alkyl carboxylic acid 中山大学 2022-10-04 CN disclosed