Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.80 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.80 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.80 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.80 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.80 |
| ▸ | DRD3 | P35462 | 1/20 | 0.80 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.80 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.51 |
| ▸ | AR | P10275 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699966 | 1.00 | PGR (0.80) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| SCHEMBL11694584 | 0.89 | PGR (0.64) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| SCHEMBL8853332 | 0.89 | PGR (0.64) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| Norgestimate SCHEMBL5523236 | 0.89 | PGR (1.00) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| Norgestimate SCHEMBL38317 | 0.89 | PGR (1.00) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| Norgestimate SCHEMBL5173707 | 0.89 | PGR (1.00) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| Norgestimate SCHEMBL633395 | 0.89 | PGR (1.00) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| Norgestimate SCHEMBL15233395 | 0.89 | PGR (1.00) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| Norgestimate SCHEMBL1411821 | 0.89 | PGR (1.00) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| Norgestimate SCHEMBL38318 | 0.89 | PGR (1.00) | PGRSLC6A4NR3C1ADORA3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027019-A | 3-Oximes of D-17α-ethynyl-19-nortestosterone esters and method | ORTHO PHARMACEUTICAL CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |