Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764670 | 0.71 | TSHR (0.56) | TSHRMAPK1TDP1CYP3A4LMNA | |
| SCHEMBL19136817 | 0.69 | PDE2A (0.36) | — | |
| SCHEMBL3043251 | 0.64 | TRPV4 (0.46) | TSHRMAPK1TDP1CYP3A4TRPV4 | |
| SCHEMBL9967733 | 0.64 | PDE2A (0.43) | LMNAHIF1A | |
| SCHEMBL27666874 | 0.63 | TSHR (0.55) | TSHRMAPK1TDP1CYP3A4LMNA | |
| SCHEMBL11701963 | 0.63 | TSHR (0.32) | TSHRMAPK1TDP1CYP3A4TRPV4 | |
| SCHEMBL19137076 | 0.62 | FAAH (0.40) | — | |
| SCHEMBL19542869 | 0.61 | LMNA (0.38) | TSHRMAPK1TDP1CYP3A4TRPV4 | |
| SCHEMBL11501808 | 0.61 | AHR (0.46) | TSHRMAPK1TDP1CYP3A4LMNA | |
| SCHEMBL20032275 | 0.60 | AKR1C3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039587-A | Method of preparing polynuclear, halogenated, aromatic benzyl ethers | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |