Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11705716 | 0.98 | ADRB2 (0.53) | ADRB2HIF1ATSHRADRA1AKDM4E | |
| SCHEMBL19330018 | 0.79 | KDM4E (0.63) | ADRB2HIF1ATSHRKDM4ECYP2C9 | |
| Norbudrine SCHEMBL2732733 | 0.79 | ADRB2 (0.65) | ADRB2HIF1ATSHRADRA1AKDM4E | |
| Norbudrine SCHEMBL29387737 | 0.79 | ADRB2 (0.65) | ADRB2HIF1ATSHRADRA1AKDM4E | |
| SCHEMBL11264601 | 0.78 | KDM4E (0.51) | ADRB2HIF1ATSHRADRA1AKDM4E | |
| Hydrochloric Acid SCHEMBL11256705 | 0.77 | LMNA (0.50) | ADRB2HIF1ATSHRADRA1AKDM4E | |
| SCHEMBL11846370 | 0.75 | KDM4E (0.48) | ADRB2KDM4EKMT2ABCHE | |
| SCHEMBL11848246 | 0.75 | KDM4E (0.48) | ADRB2KDM4EKMT2ABCHE | |
| SCHEMBL9768074 | 0.74 | ADRB2 (0.63) | ADRB2HIF1ATSHRADRA1AKDM4E | |
| SCHEMBL11644150 | 0.74 | ADRB2 (0.48) | ADRB2TSHRKDM4ECYP3A4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011258-A | ETHANOLAMINES | AKTIEBOLAGET DRACO (SW) | 1977-03-08 | — | — | US | disclosed |
| US-3937838-A | BRONCHODILATORS, DIHYDROXYPHENYL ETHANOLAMINES | AKTIEBOLAGET DRACO (SW) | 1976-02-10 | — | — | US | disclosed |