Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11256705 | 0.87 | LMNA (0.50) | KDM4EBCHEADRB2TSHRHIF1A | |
| SCHEMBL11270863 | 0.80 | KDM4E (0.52) | KDM4EBCHEMEN1KMT2AALDH1A1 | |
| SCHEMBL11701217 | 0.78 | ADRB2 (0.54) | KDM4EBCHEADRB2TSHRHIF1A | |
| SCHEMBL11263175 | 0.78 | METAP2 (0.41) | MEN1KMT2ALMNAMAPT | |
| Bromide SCHEMBL11705716 | 0.77 | ADRB2 (0.53) | KDM4EBCHEADRB2TSHRHIF1A | |
| SCHEMBL11264231 | 0.74 | LMNA (0.66) | KDM4EBCHEADRB2TSHRHIF1A | |
| SCHEMBL19330018 | 0.70 | KDM4E (0.63) | KDM4EBCHEADRB2TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL11378737 | 0.69 | KDM4E (0.51) | KDM4EBCHEADRB1ADRB3MEN1 | |
| Acetic Acid SCHEMBL19330042 | 0.69 | KDM4E (0.66) | KDM4EBCHEADRB2HIF1AADRB1 | |
| SCHEMBL11263374 | 0.68 | KDM4E (0.51) | KDM4EBCHEMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337272-A | BRONCHODILATOR AGENTS | VALEAS S. R. L. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1982-06-29 | — | — | US | disclosed |
| US-4252824-A | BRONCHODILATOR AGENTS | VALEAS S.R.L., INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1981-02-24 | — | — | US | disclosed |