Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.43 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170142 | 0.90 | PEPD (0.33) | DPP8DPP4DPP9DPP7FAP | |
| SCHEMBL3422835 | 0.75 | DPP8 (0.45) | DPP8DPP4DPP9DPP7FAP | |
| SCHEMBL2719834 | 0.71 | CYP3A4 (0.35) | ACERENRAB9ACHRNB2CHRNA5 | |
| SCHEMBL4959221 | 0.71 | GRM8 (0.62) | DPP8DPP4DPP9GRIN1GRIN2B | |
| SCHEMBL496858 | 0.71 | GRM8 (0.62) | DPP8DPP4DPP9GRIN1GRIN2B | |
| SCHEMBL14645015 | 0.70 | CYP3A4 (0.38) | DPP8DPP4DPP7RAB9ACHRNB2 | |
| SCHEMBL30716624 | 0.70 | QARS1 (0.40) | DPP8DPP4DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL10636419 | 0.69 | GRM8 (0.60) | DPP8DPP4DPP9GRIN1GRIN2B | |
| SCHEMBL11490824 | 0.69 | FKBP1A (0.49) | — | |
| SCHEMBL13601738 | 0.69 | FKBP1A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001400-B1 | ORAL FORMULATIONS OF GLYCYL-2-METHYLPROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LTD (NZ) | 2014-05-07 | — | — | EP | claimed |
| US-7887839-B2 | microemulsions, water in oil emulsion, continuous hydrophobic phase including oil, surfactant; for treatment of neurodegenerative disorders; tablets; pharmacokinetics, bioavailability | NEUREN PHARMACEUTICALS LTD. (NZ) | 2011-02-15 | — | — | US | claimed |
| US-20090074865-A1 | Oral formulations of glycyl-2-methylprolyl-glutamate | NEUREN PHARMACEUTICALS LIMITED (AU) | 2009-03-19 | — | — | US | claimed |
| EP-2001400-A2 | ORAL FORMULATIONS OF GLYCYL-2-METHYLPROLYL-GLUTAMATE | Neuren Pharmaceuticals Limited (NZ) | 2008-12-17 | — | — | EP | claimed |
| WO-2007106555-A2 | ORAL FORMULATIONS OF GLYCYL-2-METHYLPROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2007-09-20 | — | — | WO | claimed |