Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.68 |
| ▸ | NPC1 | O15118 | 12/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | PKM | P14618 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705152 | 0.90 | RAB9A (0.68) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL11703469 | 0.89 | RAB9A (0.73) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL31265132 | 0.82 | TUBB4A (0.61) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL11207978 | 0.81 | RAB9A (1.00) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL11700747 | 0.81 | NPC1 (0.69) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL11705585 | 0.80 | RAB9A (0.70) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL11706816 | 0.79 | NPC1 (1.00) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL11703485 | 0.79 | RAB9A (0.73) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL31265130 | 0.79 | LMNA (0.53) | RAB9ANPC1KMT2APKMMEN1 | |
| SCHEMBL25967687 | 0.78 | IRAK4 (0.85) | RAB9ANPC1KMT2APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |