Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304220 | 0.81 | GRIN2D (0.38) | OPRM1SIGMAR1ACHE | |
| SCHEMBL22304428 | 0.77 | SIGMAR1 (0.41) | NOS3NOS1NOS2OPRM1OPRD1 | |
| SCHEMBL11782325 | 0.77 | OPRM1 (0.34) | OPRM1 | |
| SCHEMBL24081406 | 0.76 | HRH3 (0.47) | — | |
| SCHEMBL11053451 | 0.75 | DRD2 (0.61) | DRD2DRD3ACHE | |
| SCHEMBL19791856 | 0.75 | SIGMAR1 (0.63) | DRD2DRD3SIGMAR1CHRNA7 | |
| Hydrochloric Acid SCHEMBL11222319 | 0.74 | DRD2 (0.59) | DRD2DRD3ACHE | |
| SCHEMBL21424561 | 0.74 | OPRM1 (0.49) | DRD2DRD3OPRM1OPRD1SIGMAR1 | |
| SCHEMBL22477102 | 0.74 | OPRM1 (0.49) | DRD2DRD3OPRM1OPRD1SIGMAR1 | |
| SCHEMBL24081376 | 0.74 | OPRM1 (0.49) | DRD2DRD3OPRM1OPRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049701-A | ANALGESICS, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |