Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 7/20 | 0.36 |
| ▸ | CNR2 | P34972 | 6/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701220 | 0.98 | ESR1 (0.40) | ESR1ESR2NUDT1BACE1CNR1 | |
| SCHEMBL11332988 | 0.78 | NUDT1 (0.39) | ESR1ESR2NUDT1BACE1PTGDR2 | |
| SCHEMBL11705406 | 0.77 | ESR1 (0.41) | ESR1ESR2NUDT1BACE1CNR1 | |
| SCHEMBL28494101 | 0.77 | NUDT1 (0.36) | NUDT1BACE1CNR1CNR2PTGDR2 | |
| SCHEMBL11705962 | 0.75 | PTGDR2 (0.41) | ESR1ESR2NUDT1BACE1CNR1 | |
| SCHEMBL1087151 | 0.74 | KDM4E (0.49) | ESR1ESR2NUDT1BACE1PTGDR2 | |
| SCHEMBL9804702 | 0.72 | ESR1 (0.41) | ESR1ESR2NUDT1BACE1CNR1 | |
| SCHEMBL9804524 | 0.72 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL11672196 | 0.72 | NUDT1 (0.44) | NUDT1BACE1CNR1CNR2PTGDR2 | |
| SCHEMBL19508041 | 0.71 | P2RX7 (0.33) | PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059563-A | ANTIDEGRADATION | NIPPON ZEON CO. LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4008284-A | ANTIDEGRADATION | NIPPON ZEON CO., LTD. (JA) | 1977-02-15 | — | — | US | disclosed |